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Read-through genes, such as ARPC4-TTLL3, are commonly found in mRNAseq fusion studies. Read-through genes represent physiological phenomena not related to cancer. However, from an analytical point of view, they mimic intrachromosomal, non reciprocal fusions. The processing of read-through data may thus steal resources from the analysis and may therefore slow down the whole process. To overcome this problem, FusionAnalyser allows the user to define a set of custom a priori filtering pairs, such as ARPC4 and TTLL3, that can be filtered out in the early phases of the analysis.
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